When is dose adjustment needed?

Drugs primarily cleared by the kidneys often need dose reduction or interval extension when GFR < 60 mL/min. Severely impaired function (GFR < 30) requires adjustment for most renally cleared drugs.

Which drugs commonly need renal adjustment?

Antibiotics (vancomycin, aminoglycosides, beta-lactams), anticoagulants (DOACs, enoxaparin), antidiabetics (metformin, sulfonylureas), and many cardiovascular drugs.

How is GFR estimated?

Use the CKD-EPI equation (preferred) or Cockcroft-Gault for drug dosing. Many drug labels reference CrCl (Cockcroft-Gault) rather than eGFR.

Online Medical Tools — Renal Dosing

Printed on 2/13/2026

For informational purposes only. This is not medical advice.

Pharmacy

Renal Dosing

This tool classifies renal function by GFR into standard CKD stages and provides general guidance on medication dose adjustment. It is a starting point — always consult drug-specific dosing recommendations for individual medications.

Compare with eGFR Calculator

Formula: GFR staging: Normal ≥90, Mild 60–89, Moderate 30–59, Severe 15–29, ESRD <15 mL/min/1.73m².

Estimated GFR

mL/min/1.73m²

Disclaimer: This tool is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about your health.

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